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Atherosclerosis

 

A natural part of the aging process, arteriosclerosis (thickening and hardening of the arteries) occurs more rapidly in some people than others. Atherosclerosis, a type of arteriosclerosis, occurs when fatty materials, from cholesterol and calcium, cause plaque deposits on the inner artery walls.  The plaque build-up may reduce or block blood flow to entire portions of the body. Medium and large arteries are affected and a heart attack or stroke may occur if an artery becomes completely blocked.

Causes

Research is currently being conducted on the possible roles of platelets and excess blood lipoproteins. Although the exact cause is not known, many risk factors appear to play a role in atherosclerosis development.

Risk Factors

  • High cholesterol or serum triglyceride levels

  • High blood pressure (Hypertension)

  • Smoking, particularly for atherosclerosis of coronary and leg arteries

  • Family history of vascular disease

  • Diabetes

Symptoms

Symptoms are dependent on which artery is affected.

Atherosclerosis of the Carotid artery, which supplies blood to the brain, results in temporary or permanent strokes.

The Coronary artery supplies blood to the heart muscles. Atherosclerosis can cause chest pain (angina pectoris) and as blood vessels narrow this may lead to a heart attack (myocardial infarction).

Mesenteric arteries send blood to the bowels. Atherosclerosis results in possible weight loss, abdominal pain, and/or bowel death (mesenteric infarction).

Leg artery atherosclerosis results in muscle pain after walking (claudication).

Renal arteries lead to the kidneys where blood is cleaned and urine produced. High blood pressure (hypertension) is often caused by renal atherosclerosis.

Diagnosis

Blocked arteries make a noise like water roaring over rapids. Your doctor can listen for this sound during a check-up. If blocked arteries are suspected tests can measure the amount of blood going to specific areas of the body. This helps to pinpoint the type of arteries affected. Then an Arteriogram may be performed. Arteriograms take x-ray pictures mapping any obstructions inside the artery.

Treatment

A large variety of treatment options are available to meet your individual needs. Medicines exist to dilate smaller arteries or to help lower blood cholesterol. Many medications are available for control of diabetes and hypertension.

Surgery may be needed to treat specific diseased arteries and reduce the risk of strokes and/or heart attacks.

The major types of surgery are:

  • Thromboendarterectomy: diseased inner layers of the artery are removed.

  • Embolectomy: uses an inflatable balloon catheter to remove clots on the artery wall.

  • Resection: surgical removal of an artery after an aneurysm, or wall weakening, is followed by creating a bypass with a synthetic graft.

  • Bypass: is the construction of a new artery around the blockage area without removing the diseased artery.

Prognosis

Currently there are no medicines available that cure Atherosclerosis. It may begin as early as childhood and then slowly progress.  The deadly blow may strike as early as age 30 or for others wait until their fifties or sixties. Prevention using appropriate behavioral changes in diet and exercise are tremendously effective in reducing the progress of atherosclerosis.

Prevention

The importance of lifestyle prevention practices cannot be emphasized enough as a factor in preventing cardiovascular disease. Utilize a proper diet to maintain blood cholesterol and triglyceride levels within normal limits. Lose weight, if you’re overweight. If diabetic and/or you have high blood pressure, take your medications regularly.

Please visit the following sites for more information

American Heart Association  

FDA: Keeping Cholesterol Under Control with colorful graphics explaining the cholesterol demon and how to control it.

National Heart, Lung, and Blood Institute

 

 

 

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